{"product_id":"r-ras-proteins-tgf-beta-and-cancer-von-mete-erdogan","title":"R-Ras Proteins, TGF-Beta and Cancer","description":"\u003cp\u003eDuring the progression of human cancers, normal  cells acquire genetic and epigenetic changes in the  signaling pathways that govern their proliferation,  resulting in uncontrolled growth and tumor  formation. Oncogenic Ras and Transforming Growth  Factor-Beta are known to cooperate in promoting  malignant transformation, yet the mechanism by which  they interact has not been established. Here, we  present novel mechanisms through which Transforming  Growth Factor-Beta interacts with two Ras-related  proteins, R-Ras and TC21, to transform mammary  epithelial cells.\u003c\/p\u003e\u003cdiv class=\"aw-variant-hidden-subtitle-div\" id=\"aw-variant-subtitle-9783838306643\"\u003e\u003ch3\u003eMechanisms of Interaction Among the R-Ras, TC21 and TGF-Beta Signaling Pathways\u003c\/h3\u003e\u003c\/div\u003e","brand":"Autorenwelt Shop","offers":[{"title":"Softcover - 9783838306643","offer_id":39497091842141,"sku":"9783838306643","price":49.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0940\/0622\/files\/db0563b8-e523-4ae4-bd6e-fe2b69260973.jpg?v=1773381781","url":"https:\/\/shop.autorenwelt.de\/products\/r-ras-proteins-tgf-beta-and-cancer-von-mete-erdogan","provider":"Autorenwelt Shop","version":"1.0","type":"link"}