{"product_id":"protein-homology-detection-through-alignment-of-markov-random-fields-von-jinbo-xu-sheng-wang-und-jianzhu-ma","title":"Protein Homology Detection Through Alignment of Markov Random Fields","description":"This work covers sequence-based protein homology detection, a fundamental and challenging bioinformatics problem with a variety of real-world applications. The text first surveys a few popular homology detection methods, such as Position-Specific Scoring Matrix (PSSM) and Hidden Markov Model (HMM) based methods, and then describes a novel Markov Random Fields (MRF) based method developed by the authors. MRF-based methods are much more sensitive than HMM- and PSSM-based methods for remote homolog detection and fold recognition, as MRFs can model long-range residue-residue interaction. The text also describes the installation, usage and result interpretation of programs implementing the MRF-based method.\u003cdiv class=\"aw-variant-hidden-subtitle-div\" id=\"aw-variant-subtitle-9783319149134\"\u003e\u003ch3\u003eUsing MRFalign\u003c\/h3\u003e\u003c\/div\u003e","brand":"Autorenwelt Shop","offers":[{"title":"Softcover - 9783319149134","offer_id":40083728138333,"sku":"9783319149134","price":53.49,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0940\/0622\/files\/59351251-4457-4023-8cc3-ba0566386a4b.jpg?v=1772259674","url":"https:\/\/shop.autorenwelt.de\/products\/protein-homology-detection-through-alignment-of-markov-random-fields-von-jinbo-xu-sheng-wang-und-jianzhu-ma","provider":"Autorenwelt Shop","version":"1.0","type":"link"}