{"product_id":"prefoldins-the-new-chaperones-von-undefined","title":"Prefoldins: the new chaperones","description":"This book reviews recent work on molecular chaperones of the prefoldin family from their discovery in Archaea to the basic clarification of their structure. Even though, there is still a lot to investigate in order to understand the roles and functions of prefoldins, some preliminary work suggests their contribution in assembly and activation of a variety of macromolecular complexes. Hence, the reader is introduced to recent structural findings via cryo-electron microscopy and to the importance of this particular group of proteins in health and disease.   This book also discusses the particular structure of the URI prefoldin-like complex. In addition, recent developments in the generation of URI mouse models speculate on the functions and emerging roles of the URI prefoldin-like complex in various cellular processes. This novel protein complex represents a unique cellular machinery, which molecular basis of its activity still remains to be determined.\u003cp\u003eThis work is thus a guide to help researchers in the field to have a more comprehensive and critical view of the prefoldin world.\u003c\/p\u003e\n            \u003cdiv class=\"aw-variant-hidden-subtitle-div\" id=\"aw-variant-subtitle-9783030007362\"\u003e\u003ch3\u003e\u003c\/h3\u003e\u003c\/div\u003e","brand":"Autorenwelt Shop","offers":[{"title":"Hardcover - 9783030007362","offer_id":39799870324829,"sku":"9783030007362","price":106.99,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0940\/0622\/files\/d2b02271-521e-4e6c-937b-d974f7646a77.jpg?v=1775708258","url":"https:\/\/shop.autorenwelt.de\/products\/prefoldins-the-new-chaperones-von-undefined","provider":"Autorenwelt Shop","version":"1.0","type":"link"}