{"product_id":"poliomawirusnyj-nefrit-von-meriam-khadhar-soumaq-chargui-und-dawid-buob","title":"Poliomawirusnyj nefrit","description":"\u003cp\u003ePoliomawirusnyj nefrit (PVAN) qwlqetsq odnim iz naibolee rasprostranennyh wirusnyh oslozhnenij pri transplantacii pochki. Bolee chem w 97% sluchaew on wyzywaetsq wirusom BK w kontexte BK-wirusnogo nefrita i menee chem w 2% - wirusom JC. PVAN priwodit k potere transplantata w 30-80% sluchaew. Poätomu rannqq diagnostika neobhodima dlq izmeneniq immunosupressiwnoj terapii i predotwrascheniq poteri transplantata. Diagnoz PVAN qwlqetsq gistologicheskim i sochetaet tubulointersticial'noe wospalenie i wirusnyj citopaticheskij äffekt w wide qdernyh wklüchenij tubulqrnyh kletok. Infekciq tubulqrnyh kletok mozhet byt' wydelena immunogistohimicheskimi dokazatel'stwami äxpressii wirusnogo antigena Sv-40. PVAN imeet gistologicheskoe shodstwo s ostrym kletochnym ottorzheniem, no metody lecheniq diametral'no protiwopolozhny. V odnom sluchae trebuetsq snizhenie immunosupressii, w drugom - ee powyshenie. Poätomu rannqq i tochnaq diagnostika qwlqetsq wazhnoj zadachej.\u003c\/p\u003e\u003cdiv class=\"aw-variant-hidden-subtitle-div\" id=\"aw-variant-subtitle-9786205665626\"\u003e\u003ch3\u003ePri transplantacii pochek\u003c\/h3\u003e\u003c\/div\u003e","brand":"Autorenwelt Shop","offers":[{"title":"Softcover - 9786205665626","offer_id":40919446683741,"sku":"9786205665626","price":19.8,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0940\/0622\/files\/0b79c853-8218-405e-9eab-3a2bd79ae68b.jpg?v=1758515905","url":"https:\/\/shop.autorenwelt.de\/products\/poliomawirusnyj-nefrit-von-meriam-khadhar-soumaq-chargui-und-dawid-buob","provider":"Autorenwelt Shop","version":"1.0","type":"link"}