{"product_id":"nsaids-and-drug-profile-von-pushpendra-kumar-vishwakarma","title":"NSAID's and Drug Profile","description":"\u003cp\u003eNonsteroidal anti-inflammatory drugs (NSAIDs) are a group of organic  acids that have analgesic, anti-inflammatory, and antipyretic properties.  NSAIDs are inhibitors of the enzyme cyclo-oxygenase, and so directly inhibit  the biosynthesis of prostaglandins and thromboxanes from arachidonic acid.  There are 2 forms of cyclo-oxygenase (COX), COX-1, which is the  constitutive form of the enzyme, and COX-2, which is the form induced in  the presence of inflammation. Inhibition of COX-2 is therefore thought to be  responsible for at least some of the analgesic, anti-inflammatory, and  antipyretic properties of NSAIDs whereas inhibition of COX-1 is thought to  produce some of their toxic effects, particularly those on the gastrointestinal  tract. Most of the NSAIDs currently available for clinical use inhibit both  COX-1 and COX-2, although selective COX-2 inhibitors such as celecoxib  are now available.\u003c\/p\u003e\u003cdiv class=\"aw-variant-hidden-subtitle-div\" id=\"aw-variant-subtitle-9783845415437\"\u003e\u003ch3\u003e\u003c\/h3\u003e\u003c\/div\u003e","brand":"Autorenwelt Shop","offers":[{"title":"Softcover - 9783845415437","offer_id":39471379513437,"sku":"9783845415437","price":59.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0940\/0622\/files\/86612558-07dc-430b-8184-c373f549ae24.jpg?v=1770448599","url":"https:\/\/shop.autorenwelt.de\/products\/nsaids-and-drug-profile-von-pushpendra-kumar-vishwakarma","provider":"Autorenwelt Shop","version":"1.0","type":"link"}