{"product_id":"notch-signaling-and-stromal-microenvironment-in-acute-leukemia-von-armel-herve-nwabo-kamdje","title":"Notch signaling and stromal microenvironment in acute leukemia","description":"\u003cp\u003eNotch signaling pathway regulates many different events of embryonic and adult development:  among them, Notch plays an essential role in the onset of hematopoietic stem cells and influences  multiple maturation steps of developing lymphoid and myeloid cells. Deregulation of Notch  signaling determines several human disorders, including cancer. In the last decade it became  evident that Notch signaling plays pivotal roles in the onset and development of acute leukemia by regulating the intracellular molecular pathways involved in leukemia.  Here, the data concerning acute leukemia and bone marrow stromal cells has been critically reviewed in light of the most recent findings on Notch signaling in stromal  microenvironment.\u003c\/p\u003e\u003cdiv class=\"aw-variant-hidden-subtitle-div\" id=\"aw-variant-subtitle-9783846530627\"\u003e\u003ch3\u003eRole of Notch in acute leukemia\u003c\/h3\u003e\u003c\/div\u003e","brand":"Autorenwelt Shop","offers":[{"title":"Softcover - 9783846530627","offer_id":39471223537757,"sku":"9783846530627","price":49.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0940\/0622\/files\/39a7f433-5ad8-4bea-9966-1d00e8cf55c5.jpg?v=1776055376","url":"https:\/\/shop.autorenwelt.de\/products\/notch-signaling-and-stromal-microenvironment-in-acute-leukemia-von-armel-herve-nwabo-kamdje","provider":"Autorenwelt Shop","version":"1.0","type":"link"}