Neuroimaging and Early Diagnosis of Alzheimer Disease: Alzheimer Disease

Neuroimaging and Early Diagnosis of Alzheimer Disease: Alzheimer Disease


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von Mohammad Mohsin Khan, Mustafa Siddiqui, Khadija Raza

Beschreibung

Alzheimer disease (AD), a progressive neurodegenerative disorder, is the most common cause of dementia in the elderly. Current consensus statements have emphasized the need for early recognition and the fact that a diagnosis of AD can be made with high accuracy by using clinical, neuropsychologic, and imaging assessments. Magnetic resonance (MR) or computed tomographic (CT) imaging is recommended for the routine evaluation of AD. Coronal MR images can be useful to document or quantify atrophy of the hippocampus and entorhinal cortex, both of which occur early in the disease process. Both volumetric and subtraction MR techniques can be used to quantify and monitor dementia progression and rates of regional atrophy. MR measures are also increasingly being used to monitor treatment effects in clinical trials of cognitive enhancers and antidementia agents. Positron emission tomography (PET) and single photon emission CT offer value in the differential diagnosis of AD from other cortical and subcortical dementias and may also offer prognostic value.


Tags: Medizin, Klinische Fächer


Taschenbuch - 9783639372014
Verlag: VDM Verlag
Ersterscheinung: Juli 2011
ISBN-13: 9783639372014
Größe: 220 mm x 150 mm x 5 mm
Gewicht: 136 Gramm
80 Seiten
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