{"product_id":"molecular-neurosurgery-with-targeted-toxins-von-douglas-a-lappi-ronald-g-wiley-hrsg","title":"Molecular Neurosurgery with Targeted Toxins","description":"Pioneers and leading researchers explain the theory and techniques of using targeted toxins experimentally. The highly successful use of the 192 IgG-saporin and ME20.4-saporin immunotoxins to lesion the cholinergic basal forebrain in order to model the behavior, anatomy, physiology, and pharmacology of Alzheimer's disease in animals is treated in detail to give a potential user the knowledge to comfortably use the techniques involved. The uses of important new lesioning agents such as anti-DBH-saporin immunotoxin to make remarkably selective lesions of catecholaminergic neurons, hypocretin-saporin that can produce narcoleptic animals, and other saporin conjugates, such as neuropeptide-saporin conjugates for pain research and cholera toxin B chain-saporin to produce a model of CNS demyelination are explained by experts in the field.\u003cdiv class=\"aw-variant-hidden-subtitle-div\" id=\"aw-variant-subtitle-9781588291998\"\u003e\u003ch3\u003e\u003c\/h3\u003e\u003c\/div\u003e\u003cdiv class=\"aw-variant-hidden-subtitle-div\" id=\"aw-variant-subtitle-9781617374203\"\u003e\u003ch3\u003e\u003c\/h3\u003e\u003c\/div\u003e","brand":"Libri","offers":[{"title":"Hardcover - 9781588291998","offer_id":51117837254,"sku":"9781588291998","price":181.89,"currency_code":"EUR","in_stock":true},{"title":"Softcover - 9781617374203","offer_id":39417616138333,"sku":"9781617374203","price":128.39,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0940\/0622\/files\/ee7ed795-e738-4f7e-8bd0-ee6059c3d0e0.jpg?v=1778905147","url":"https:\/\/shop.autorenwelt.de\/products\/molecular-neurosurgery-with-targeted-toxins-von-douglas-a-lappi-ronald-g-wiley-hrsg","provider":"Autorenwelt Shop","version":"1.0","type":"link"}