{"product_id":"modulation-of-sialidases-in-pancreatic-cancer-von-shalini-nath","title":"Modulation Of Sialidases In Pancreatic Cancer","description":"\u003cp\u003ePancreatic cancer is one of the deadliest forms of cancer with a very low survival rate. Sialidases are enzymes that play a key role in cancer progression by cleaving sialic acid residues from glycoproteins and glycolipids. The modulation of sialidases in pancreatic cancer has gained considerable attention as a potential therapeutic target for inhibiting tumor growth, invasion, and metastasis.\u003c\/p\u003e\u003cp\u003eIn recent years, research has focused on understanding the mechanisms of sialidase modulation and its impact on tumor biology. Studies have identified sialylated glycans and tumor-associated carbohydrate antigens as important biomarkers for diagnosis and prognosis. Additionally, sialidase modulation has been shown to affect cancer cell signaling pathways, apoptosis, chemoresistance, and immune response.\u003c\/p\u003e\u003cp\u003eThe tumor microenvironment, including extracellular matrix, stromal cells, and immune cells, plays a critical role in pancreatic cancer progression. Sialidase modulation has been shown to impact the tumor microenvironment by influencing the behavior of cancer-associated fibroblasts, tumor-infiltrating lymphocytes, and angiogenesis.\u003c\/p\u003e\u003cp\u003eEmerging evidence suggests that sialidase modulation may have significant implications for personalized cancer treatment and precision medicine. Furthermore, the identification of novel therapeutic targets and the development of glycan-targeted therapeutics offer exciting prospects for the development of new and effective treatments for pancreatic cancer.\u003c\/p\u003e\u003cdiv class=\"aw-variant-hidden-subtitle-div\" id=\"aw-variant-subtitle-9781865814025\"\u003e\u003ch3\u003e\u003c\/h3\u003e\u003c\/div\u003e","brand":"Autorenwelt Shop","offers":[{"title":"Softcover - 9781865814025","offer_id":46364157280581,"sku":"9781865814025","price":54.8,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0940\/0622\/files\/1e48206d-f4f4-49e4-bffe-fcc07da4d8e2.jpg?v=1776141272","url":"https:\/\/shop.autorenwelt.de\/products\/modulation-of-sialidases-in-pancreatic-cancer-von-shalini-nath","provider":"Autorenwelt Shop","version":"1.0","type":"link"}