{"product_id":"modelling-atherosclerosis-von-nader-el-khatib","title":"Modelling Atherosclerosis","description":"\u003cp\u003eAtherosclerosis is an inflammatory disease which  starts when low density lipoproteins (LDL) enter the  intima of blood vessel where they are oxidized  (ox-LDL). The ox-LDL is considered as a dangerous  agent by the immune system provoking an  anti-inflammatory response. This immune response  triggers the recruitment of monocytes into the intima  where they differentiate into macrophages and foam  cells. The latter amplifies the production of  inflammatory cytokines and further recruitment of  monocytes. This auto-amplified process is compensated  by the secretion of anti-inflammatory cytokines  biochemical anti-inflammation) and triggers the  migration of smooth muscle cells to form a fibrous  cap that covers the lipid core. These fibrous caps  with the lipid core are called atherosclerosis  plaque. It changes the geometry of the blood vessel  by narrowing it and interacts with the blood flow.  This interaction may have dangerous consequences  related to the plaque rupture or to the formation of  blood clot. This book is devoted to mathematical  modelling ofthese phenomena.\u003c\/p\u003e\u003cdiv class=\"aw-variant-hidden-subtitle-div\" id=\"aw-variant-subtitle-9786131527982\"\u003e\u003ch3\u003eTowards the Mathematical Prediction\u003c\/h3\u003e\u003c\/div\u003e","brand":"Autorenwelt Shop","offers":[{"title":"Softcover - 9786131527982","offer_id":40149229109341,"sku":"9786131527982","price":39.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0940\/0622\/files\/a6ff4479-8d31-4030-805c-bc6b5c4c0f16.jpg?v=1777008547","url":"https:\/\/shop.autorenwelt.de\/products\/modelling-atherosclerosis-von-nader-el-khatib","provider":"Autorenwelt Shop","version":"1.0","type":"link"}