{"product_id":"method-development-and-validation-for-voriconazole-estimation-von-yarguntla-srinivasa-rao-und-k-vara-prasada-rao","title":"Method Development and Validation for Voriconazole Estimation","description":"\u003cp\u003eA rapid, sensitive, and specific RP-HPLC method with UV detection was developed and validated for the determination of voriconazole. Chromatography was performed on an Enable C18 G column (250 × 4.6 mm) in isocratic mode, using a mobile phase of methanol and acetonitrile (60:40, v\/v). The flow rate was set at 1 mL\/min, and the effluent was monitored at 223 nm. Chromatographic analysis revealed a main peak for voriconazole at a retention time of 2.841 minutes. Methanol was selected as the solvent for the analysis, with the ¿max determined to be 223 nm. The method exhibited linearity over a concentration range of 5-30 µg\/mL. Validation parameters, including linearity, range, precision, accuracy, limit of detection (LOD), and limit of quantitation (LOQ), were assessed and met the required standards.\u003c\/p\u003e\u003cdiv class=\"aw-variant-hidden-subtitle-div\" id=\"aw-variant-subtitle-9783330051331\"\u003e\u003ch3\u003eRP-HPLC and UV Spectrophotometric Methods in Bulk and Pharmaceutical Formulations\u003c\/h3\u003e\u003c\/div\u003e","brand":"Autorenwelt Shop","offers":[{"title":"Softcover - 9783330051331","offer_id":53834936680773,"sku":"9783330051331","price":43.9,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0940\/0622\/files\/f2926137-122a-466d-9ee2-3a0503992a33.jpg?v=1769664242","url":"https:\/\/shop.autorenwelt.de\/products\/method-development-and-validation-for-voriconazole-estimation-von-yarguntla-srinivasa-rao-und-k-vara-prasada-rao","provider":"Autorenwelt Shop","version":"1.0","type":"link"}