{"product_id":"macromolecular-aminoquinolines-as-potential-antimalarial-drugs-von-blessing-aderibigbe","title":"Macromolecular aminoquinolines as potential antimalarial drugs","description":"\u003cp\u003eThe research in this book is focused on the application of the concept of polymer-drug conjugation to prepare conjugates. These conjugates acts as pro-drugs from which bioactive agents are released to predestined biological environment. The macromolecular carriers used are biodegradable, non-toxic, easily conveyed to the target cells or tissues, with different solubilizing groups to ensure rapid dissipation of the conjugate in the central circulation system. The polymer-drug connective link is to provide delayed and controlled drug release thereby ensuring restriction of drug serum concentration and reduction of organ toxicity.  This book elaborates on the conjugation of 4- and 8-aminoquinolines to polymers to overcome the drug resistance associated with the currently used aminoquinolines. Presently, some antimalarial drugs have been found to be anti-carcinogenic and have ability to inhibit tumor development and as such, this book is also focused on the co-conjugation of an anticancer and an antimalarial agent on a single carrier, whereby the antimalarial is expected to serve as potentiating and resistance reducing agent.\u003c\/p\u003e\u003cdiv class=\"aw-variant-hidden-subtitle-div\" id=\"aw-variant-subtitle-9783846529782\"\u003e\u003ch3\u003eMacromolecular 4- and 8-aminoquinoline compounds\u003c\/h3\u003e\u003c\/div\u003e","brand":"Autorenwelt Shop","offers":[{"title":"Softcover - 9783846529782","offer_id":39471372468317,"sku":"9783846529782","price":68.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0940\/0622\/files\/8201e1bd-7f0a-4082-818c-48286aed23ab.jpg?v=1772867654","url":"https:\/\/shop.autorenwelt.de\/products\/macromolecular-aminoquinolines-as-potential-antimalarial-drugs-von-blessing-aderibigbe","provider":"Autorenwelt Shop","version":"1.0","type":"link"}