{"product_id":"lgl-regulates-cell-cycle-progression-in-drosophila-von-nancy-amin","title":"Lgl regulates cell cycle progression in Drosophila","description":"\u003cp\u003eThis thesis focuses on a gene, lgl identified in a  genetic interaction screen for novel negative  regulators of G1 to S phase progression. The screen  was  carried out by isolating dominant suppressors of a  Drosophila hypomorphic mutant of the key G1 to S  phase  regulator cyclin E, DmcycEJP. lgl (lethal giant  larvae)  is a tumour suppressor with a known role in  epithelial  and neuroblast cell polarity. This thesis''aim is to uncover the mechanisms by which the tumour  suppressor  Lgl functions to coordinate epithelial polarity and  cell proliferation. Knowledge that will lead to the  better understanding of the process of  tumourigenesis.\u003c\/p\u003e\u003cdiv class=\"aw-variant-hidden-subtitle-div\" id=\"aw-variant-subtitle-9783838321707\"\u003e\u003ch3\u003eIdentification of a novel role for lgl in the regulation of the G1-S phase progression in  Drosophila\u003c\/h3\u003e\u003c\/div\u003e","brand":"Autorenwelt Shop","offers":[{"title":"Softcover - 9783838321707","offer_id":39469143556189,"sku":"9783838321707","price":68.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0940\/0622\/files\/8c2048c2-27e1-4d78-836e-3d65d6dadb79.jpg?v=1758173877","url":"https:\/\/shop.autorenwelt.de\/products\/lgl-regulates-cell-cycle-progression-in-drosophila-von-nancy-amin","provider":"Autorenwelt Shop","version":"1.0","type":"link"}