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Phycotoxin Okadaic acid can cause Diarrhetic shellfish poisoning syndrome, accumulates in bivalves, are potent phosphatase inhibitors produced by Dinophysis species, in acute cases killer but its carcinogenic in chronic cases. impacts health and economy, many conditions effect our Coastal and Marine Environment which coast a lot of Money in every year in many parts of world. Harmful algal bloom HABs which concerned internationally and considered as wide world phenomenon is main Main source of these types of marine biogenic toxins and other types not less than of its gravity, also cause fish mortality and bad smell of water. pollution and adding large quantity of pollutants Such as Nitrogen N and Phosphorous P also materials as minor nutrition's. OA and its isomers Dinophysistoxins (DTX1, DTX2 DTX3) are Detected in many parts of world. and Dinophysis saculus is one of (OA) producers, which is one of phytoplankton species,Distribute in North Adriatic Sea, Portugal, North Atlantic Ocean, Most often observed in semi-enclosed basins, estuaries and lagoons and Mediterranean Sea, cold and temperate waters.