{"product_id":"interferon-gamma-a-marker-of-tuberculosis-mediated-immune-response-von-shahid-hussain-und-nadeem-afzal","title":"Interferon-Gamma: A marker of tuberculosis mediated immune response","description":"\u003cp\u003eBackground: Interferon gamma (IFN-¿), a cytokine produced by a variety of cells is involved in the immune response against M.tuberculosis. It activates the production of other cytokines \u0026amp; molecules that kill MTB. IFN-¿ also has diagnostic role in identification of active and latent TB. Objective: To determine the level of IFN-¿ in the blood of TB patients. Methods: 91 subjects were selected, including 54 active TB patients and 37 healthy controls. IFN-¿ conc. was determined in their blood by ELISA technique. Results: In TB patients, Mean+SD of IFN-¿ was 48.69+28.78 while it was 12.99+5.70 pg\/ml in control group (p \u0026lt;0.001). Significant differences in the level of IFN-¿ were observed among confirmed TB patients, clinically diagnosed TB patients and the control group (Mean+SD 59.68+28.78, 36.85+24.76 and 12.99+5.70 pg\/ml, respectively). Furthermore, a significant negative correlation was observed b\/w conc. of IFN-¿ in TB patients and the duration of anti-tuberculosis therapy. Conclusion: IFN-¿ level was high in both clinically diagnosed and confirmed TB patients as compared to a control group. Measurement of IFN-¿ is helpful to diagnose active TB, but further research is required.\u003c\/p\u003e\u003cdiv class=\"aw-variant-hidden-subtitle-div\" id=\"aw-variant-subtitle-9783659372407\"\u003e\u003ch3\u003eUniversity of Health Sciences, Lahore, Pakistan\u003c\/h3\u003e\u003c\/div\u003e","brand":"Autorenwelt Shop","offers":[{"title":"Softcover - 9783659372407","offer_id":39484131147869,"sku":"9783659372407","price":35.9,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0940\/0622\/files\/675c8145-d824-476a-8387-9612f1cf7bb6.jpg?v=1773728062","url":"https:\/\/shop.autorenwelt.de\/products\/interferon-gamma-a-marker-of-tuberculosis-mediated-immune-response-von-shahid-hussain-und-nadeem-afzal","provider":"Autorenwelt Shop","version":"1.0","type":"link"}