{"product_id":"in-cell-approaches-in-electron-paramagnetic-resonance-spectroscopy-in-cell-approaches-in-electron-paramagnetic-resonance-spectroscopy-to-study-conformations-of-dna-g-quadruplexes-von-mykhailo-azarkh","title":"In-cell approaches in electron paramagnetic resonance spectroscopy","description":"\u003cp\u003eDouble electron electron resonance (DEER) is an EPR technique which allows for distance measurements on the nanometer scale. Here, EPR-based distance measurements were extended to in-cell applications. From evaluation of nitroxides for experiments in intracellular environment of Xenopus laevis oocytes and through proof-of-principle experiments optimal parameters for performing in-cell DEER were found. On the example of G-quadruplexes formed by oligomers of human telomeric DNA, DEER was shown to be applicable for structural identification of biological objects under their native conditions.\u003c\/p\u003e\u003cdiv class=\"aw-variant-hidden-subtitle-div\" id=\"aw-variant-subtitle-9783838134406\"\u003e\u003ch3\u003eIn-cell approaches in electron paramagnetic resonance spectroscopy to study conformations of DNA G-quadruplexes\u003c\/h3\u003e\u003c\/div\u003e","brand":"Libri","offers":[{"title":"Softcover - 9783838134406","offer_id":39436083691613,"sku":"9783838134406","price":69.9,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0940\/0622\/files\/027ee6b6-b97e-412a-99b6-86e61a02913e.jpg?v=1776318928","url":"https:\/\/shop.autorenwelt.de\/products\/in-cell-approaches-in-electron-paramagnetic-resonance-spectroscopy-in-cell-approaches-in-electron-paramagnetic-resonance-spectroscopy-to-study-conformations-of-dna-g-quadruplexes-von-mykhailo-azarkh","provider":"Autorenwelt Shop","version":"1.0","type":"link"}