{"product_id":"immunohistochemical-study-of-her-2-neu-and-e-cadherin-in-colon-carcinoma-von-hanan-alshenawy","title":"IMMUNOHISTOCHEMICAL STUDY OF HER-2\/neu AND E-CADHERIN IN colon CARCINOMA","description":"\u003cp\u003eColorectal cancer is one of the  most common malignant diseases worldwide. Because  the development of anti-tumor agents,  therapeutic options have considerably improved.  we Studied the expression of E-cadherin and Her- 2\/neu in colon carcinoma trying to correlate between  their expression and the prognosis of this  disease.100 specimens of colorectal carcinomas  were subjected to H\u0026amp;E staining and  immunohistochemical staining for E-cadherin and  Her2\/neu. E-cadherin expression in colorectal  carcinoma seemed to pass in chronological stages  starting from its gradual absence from the membrane  then its appearance in the cytoplasm and lastly its  total loss. Also the over-expression of Her-2\/neu  protein and its positive relation with the poor  prognostic variables may favor its role as  prognostic marker in colorectal carcinoma and may  become of great value in predicting the poor out  come of the tumour. So both agents may act as  prognostic markers to forecast the clinical course  and outcome in colon cancer and as a predictive  marker to predict the therapeutic response.\u003c\/p\u003e\u003cdiv class=\"aw-variant-hidden-subtitle-div\" id=\"aw-variant-subtitle-9783843394116\"\u003e\u003ch3\u003eIMMUNOPATHOLOGY\u003c\/h3\u003e\u003c\/div\u003e","brand":"Autorenwelt Shop","offers":[{"title":"Softcover - 9783843394116","offer_id":39470012923997,"sku":"9783843394116","price":79.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0940\/0622\/files\/9e493f53-5a31-425f-aabb-855d8ff9e1c2.jpg?v=1769148892","url":"https:\/\/shop.autorenwelt.de\/products\/immunohistochemical-study-of-her-2-neu-and-e-cadherin-in-colon-carcinoma-von-hanan-alshenawy","provider":"Autorenwelt Shop","version":"1.0","type":"link"}