{"product_id":"hno-adducts-of-horse-myoglobin-and-human-hemoglobin-generation-reactivity-reaction-rates-von-dmitry-pervitsky","title":"HNO ADDUCTS OF HORSE MYOGLOBIN AND HUMAN HEMOGLOBIN","description":"\u003cp\u003eThe first chapter is a summary of recent publications about the effect of HNO in the cardiovascular system, detection of HNO in vitro, and physiological reactivity of HNO. The second chapter provides synthetic details of a newly developed method of a synthesis of HNO-Mb of high purity (\u0026gt; 95%). The transient absorbance studies of HNO-Mb revealed completely different results than that of other myoglobin adducts such as MbO2 and NO- Mb. Formation of the Mb-Fe(III)\/HNO- geminate pair was confirmed by analyses of transient absorbance spectra at 395 nm. In the third chapter rate constants of the reaction of HNO with Mb-Fe(II), Mb- Fe(III), HNO-Mb, and HNO-Mb with oxygen and nitric oxide were determined using the computational software React for Windows. In addition to the computational method, a direct method of comparison of the rates of the reaction of HNO with proteins was developed. In the last chapter synthesis of HNO adduct of hemoglobin is reported. UV-vis, EPR, and 1H NMR spectroscopic techniques were used to identify and differentiate the hydride peaks of HNO subunits of hemoglobin.\u003c\/p\u003e\u003cdiv class=\"aw-variant-hidden-subtitle-div\" id=\"aw-variant-subtitle-9783838301587\"\u003e\u003ch3\u003eGeneration, Reactivity, Reaction Rates...\u003c\/h3\u003e\u003c\/div\u003e","brand":"Libri","offers":[{"title":"Softcover - 9783838301587","offer_id":39447155212381,"sku":"9783838301587","price":49.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0940\/0622\/files\/3833318f-f92f-480c-802f-475228307acf.jpg?v=1773382778","url":"https:\/\/shop.autorenwelt.de\/products\/hno-adducts-of-horse-myoglobin-and-human-hemoglobin-generation-reactivity-reaction-rates-von-dmitry-pervitsky","provider":"Autorenwelt Shop","version":"1.0","type":"link"}