{"product_id":"hiv-1-genome-variations-molecular-study-and-economical-solutions-von-arpan-acharya-rabindra-nath-misra-pratap-n-mukhopadhyaya","title":"HIV-1 Genome Variations: Molecular Study and Economical Solutions","description":"\u003cp\u003eThe objective of the research work described in this book was to develop molecular tools that can assist clinicians in taking more informed therapeutic decisions towards their HIV-1 infected patients. We demonstrated use of partial HIV-1 p24 gene sequence can function as a tool for viral subtyping. We report a HIV-1 viral load assay which is robust, reliable, economical and effective in resource limited settings like India. Through an extensive study spanning across 206 HIV-1 RT gene sequences, an effective and economical HIV-1 drug resistance genotyping method was developed and clinically validated. A primer extension-based process was explored for its ability to interrogate clinically important single nucleotide polymorphisms within the HIV-1 genome thus indicating its potential to be a cost effective, sensitive and specific HIV-1 mutation detection system. Finally we described a HCV genotyping assay, which has potential to influence therapeutic decisions in HIV-1\/HCV co-infected patients. Our work will add value to the existing set of tools available for an inclusive management of HIV-1 that include HCV as a co-infection.\u003c\/p\u003e\u003cdiv class=\"aw-variant-hidden-subtitle-div\" id=\"aw-variant-subtitle-9783659888175\"\u003e\u003ch3\u003e\u003c\/h3\u003e\u003c\/div\u003e","brand":"Libri","offers":[{"title":"Softcover - 9783659888175","offer_id":39450079527005,"sku":"9783659888175","price":64.9,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0940\/0622\/files\/e5da2ddb-7275-42d5-b393-a038c6adff53.jpg?v=1774594949","url":"https:\/\/shop.autorenwelt.de\/products\/hiv-1-genome-variations-molecular-study-and-economical-solutions-von-arpan-acharya-rabindra-nath-misra-pratap-n-mukhopadhyaya","provider":"Autorenwelt Shop","version":"1.0","type":"link"}