{"product_id":"heteroaromatic-lipoxin-a4-analogues-synthesis-and-biological-evaluation-von-colm-duffy","title":"Heteroaromatic Lipoxin A4 Analogues","description":"\n                                \n                \u003cp\u003eIn this thesis Colm Duffy reviews the chemistry and biology of stable lipoxin analogues. Colm has prepared for the first time ever a pyridine-containing LXA4 analogue in enantiomerically pure form. Biological evaluation determined that both epimers at the benzylic position suppress key cytokines known to be involved in inflammatory disease, with the (R)-epimer proving most efficacious. Moreover the author developed an excellent route to a related thiophene-containing analogue that also showed interesting biological activity. Both routes have inspired further work in  the synthesis of further heteroaromatic analogues for biological evaluation. \u003c\/p\u003e\n                            \n            \u003cdiv class=\"aw-variant-hidden-subtitle-div\" id=\"aw-variant-subtitle-9783642246319\"\u003e\u003ch3\u003eSynthesis and Biological Evaluation\u003c\/h3\u003e\u003c\/div\u003e\u003cdiv class=\"aw-variant-hidden-subtitle-div\" id=\"aw-variant-subtitle-9783642438929\"\u003e\u003ch3\u003eSynthesis and Biological Evaluation\u003c\/h3\u003e\u003c\/div\u003e","brand":"Libri","offers":[{"title":"Hardcover - 9783642246319","offer_id":40567123542109,"sku":"9783642246319","price":106.99,"currency_code":"EUR","in_stock":true},{"title":"Softcover - 9783642438929","offer_id":39432060141661,"sku":"9783642438929","price":106.99,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0940\/0622\/files\/759a8a9d-2f10-4279-a8b0-cb355d0d9b60.jpg?v=1775279729","url":"https:\/\/shop.autorenwelt.de\/products\/heteroaromatic-lipoxin-a4-analogues-synthesis-and-biological-evaluation-von-colm-duffy","provider":"Autorenwelt Shop","version":"1.0","type":"link"}