{"product_id":"heme-oxygenase-and-hypertension-von-joseph-fomusi-ndisang-und-ashok-b-jadhav","title":"Heme oxygenase and Hypertension","description":"\u003cp\u003eOne of the biggest health challenges in  industrialized and developing nations today is the  high incidence and rapidly growing problem of  hypertension. Hypertension is a multifactorial  disease and considered the prevalent risk factor for  many cardiovascular complications including  myocardial infarction, cardiac failure, and coronary  and peripheral artery diseases. Many hypertensive  patients are salt-sensitive. Generally, the hormone,  aldosterone regulates water\/salt balance. An  experimental model in which hypertension is  triggered by excess aldosterone and high salt intake  is the deoxycorticosterone acetate (DOCA)-salt- induced hypertension.  This book highlights the cytoprotective effects of  the heme oxygenase enzymatic pathway in  hypertension. The role of the heme oxygenase system  against hypertension, hypertrophy and fibrosis as  well as the mechanisms involved in the heme  oxygenase-mediated protection including, the  suppression of transcription factors like nuclear- factor kappaB and activating-protein-1, and the  reduction of extracellular matrix\/remodeling  proteins like fibronectin and collagen are  discussed.\u003c\/p\u003e\u003cdiv class=\"aw-variant-hidden-subtitle-div\" id=\"aw-variant-subtitle-9783838385624\"\u003e\u003ch3\u003ePotentials of heme oxygenase pathway\u003c\/h3\u003e\u003c\/div\u003e","brand":"Autorenwelt Shop","offers":[{"title":"Softcover - 9783838385624","offer_id":39469232455773,"sku":"9783838385624","price":68.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0940\/0622\/files\/a1e9be8c-475a-43ea-99d7-966340ab2146.jpg?v=1775622671","url":"https:\/\/shop.autorenwelt.de\/products\/heme-oxygenase-and-hypertension-von-joseph-fomusi-ndisang-und-ashok-b-jadhav","provider":"Autorenwelt Shop","version":"1.0","type":"link"}