{"product_id":"gram-negative-bacilli-isolated-from-the-hospital-environment-von-manel-debabza-und-abdelbasset-mechai","title":"Gram-negative bacilli isolated from the hospital environment","description":"\u003cp\u003eIn this study, 306 Gram-negative bacilli (GNB) strains were isolated from the hospital environment, 74.51% of them enterobacteria. Antibiotic susceptibility testing revealed resistance to various families of antibiotics, in particular ¿-lactam antibiotics, although imipenem, aminoglycosides and fluoroquinolones were remarkably effective. Extended-spectrum beta-lactamase (ESBL) detection tests were used to characterize 114 strains of ESBL-producing Enterobacteriaceae (EBLSE). Analysis of plasmid profiles showed that multi-resistant strains host 1 to 4 plasmids ranging from 1Kb to 170Kb. Conjugation experiments showed co-transfer of gentamicin and cotrimoxazole resistance to plasmids of 10Kb, 20Kb, 125Kb or 165Kb. PCR of transconjugating strains detected the bla CTX-M-1, bla TEM and bla SHV genes, as well as the qnrB genes. This study shows that the hospital environment is contaminated by multi-resistant BGN, particularly EBLSE, and that it can be a potential source of epidemics, prompting recommendations to be made within health facilities.\u003c\/p\u003e\u003cdiv class=\"aw-variant-hidden-subtitle-div\" id=\"aw-variant-subtitle-9786207044122\"\u003e\u003ch3\u003ePhenotypic and molecular characterization of antibiotic resistance\u003c\/h3\u003e\u003c\/div\u003e","brand":"Autorenwelt Shop","offers":[{"title":"Softcover - 9786207044122","offer_id":47525234901317,"sku":"9786207044122","price":91.9,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0940\/0622\/files\/aaf05cd1-a917-46f2-a55a-960908e5d1e2.jpg?v=1749445313","url":"https:\/\/shop.autorenwelt.de\/products\/gram-negative-bacilli-isolated-from-the-hospital-environment-von-manel-debabza-und-abdelbasset-mechai","provider":"Autorenwelt Shop","version":"1.0","type":"link"}