{"product_id":"genotipirowanie-hla-i-autoimmunnyj-gepatit-von-marua-chauali","title":"Genotipirowanie HLA i autoimmunnyj gepatit","description":"\u003cp\u003eAutoimmunnyj gepatit - äto hronicheskoe wospalitel'noe zabolewanie pecheni, woznikaüschee w rezul'tate poteri immunologicheskoj tolerantnosti k normal'nym antigenam gepatocitow. Dannoe issledowanie osnowano na opredelenii allelej i gaplotipow genow DRB1 i DQB1, powyshaüschih wospriimchiwost' k VGA, i protektiwnyh allelej i gaplotipow, a takzhe na poiske associacii mezhdu äxpressiej opredelennyh HLA-allelej s klinicheskimi proqwleniqmi zabolewaniq Tridcat' wzroslyh tunisskih pacientow s HAI proshli proceduru tipirowaniq HLA klassa II s ispol'zowaniem metoda SSP PCR. Byla obnaruzhena znachitel'naq associaciq HAI s HLA DRB1*03 s chastotoj 56,7% u pacientow po srawneniü s kontrolem. Zaschitnyj allel' dlq HAI, HLA DRB1*11, byl obnaruzhen so znachitel'no snizhennoj chastotoj u pacientow po srawneniü s kontrolem (6,7% u pacientow po srawneniü s 25% u kontrolq). Luchshee ponimanie immunologicheskih mehanizmow, wowlechennyh w autoimmunnyj gepatit, weroqtno, priwedet k bolee äffektiwnomu celenaprawlennomu lecheniü.\u003c\/p\u003e\u003cdiv class=\"aw-variant-hidden-subtitle-div\" id=\"aw-variant-subtitle-9786205536957\"\u003e\u003ch3\u003eHLA i autoimmunnyj gepatit\u003c\/h3\u003e\u003c\/div\u003e","brand":"Autorenwelt Shop","offers":[{"title":"Softcover - 9786205536957","offer_id":40839893221469,"sku":"9786205536957","price":19.8,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0940\/0622\/files\/3463c067-7023-4856-85bf-178f435756bb.png?v=1758515816","url":"https:\/\/shop.autorenwelt.de\/products\/genotipirowanie-hla-i-autoimmunnyj-gepatit-von-marua-chauali","provider":"Autorenwelt Shop","version":"1.0","type":"link"}