{"product_id":"genomic-deletions-in-patients-with-complex-phenotypes-von-chiara-pescucci","title":"Genomic deletions in patients with complex phenotypes","description":"\u003cp\u003eChromosomal abnormalities are a major cause of mental retardation and congenital malformations. It is known that a considerable fraction of patients with multiple congenital anomalies and mental retardation have submicroscopic chromosomal imbalances. The introduction of whole genome array-CGH allows to investigate the DNA for the presence of copy number alterations with high resolution. In patients with multiple congenital anomalies and mental retardation 15-24% of segmental aneusomies were reported. Given these data, we have decided to apply both classical approaches and innovative methodologies to the study of several patients with mental retardation and congenital anomalies.\u003c\/p\u003e\u003cdiv class=\"aw-variant-hidden-subtitle-div\" id=\"aw-variant-subtitle-9783659244087\"\u003e\u003ch3\u003eFrom cytogenetics to arrayCGH\u003c\/h3\u003e\u003c\/div\u003e","brand":"Autorenwelt Shop","offers":[{"title":"Softcover - 9783659244087","offer_id":39486527242333,"sku":"9783659244087","price":49.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0940\/0622\/files\/2010e5c3-e862-4b4f-a180-f1769d73e98a.jpg?v=1773382766","url":"https:\/\/shop.autorenwelt.de\/products\/genomic-deletions-in-patients-with-complex-phenotypes-von-chiara-pescucci","provider":"Autorenwelt Shop","version":"1.0","type":"link"}