{"product_id":"genetic-risk-factors-in-alzheimers-disease-von-agnes-feher","title":"Genetic risk factors in Alzheimer''s disease","description":"\u003cp\u003eAlzheimer''s disease is a progressive  neurodegenerative disorder representing the most  common type of dementia in the elderly population.  According to the complex genetic model of late- onset, non-familial Alzheimer''s disease, several  heterogeneous susceptibility sets of genes may  converge on the pathological processes that underlie  the disease. Despite decades of intensive research  the gene coding for apolipoprotein E is so far the  only widely confirmed genetic risk factor for late- onset Alzheimer''s disease. In this book we report  the results of association studies investigating  candidate gene variants supposed to be involved in  Alzheimer''s disease aetiology. Hypotheses regarding  the role of the genes in the pathogenic pathways are  discussed, taking into account the chromosomal  localizations and the functions of the encoded  proteins. As a long-term goal, identifying the  genetic risk factors would help develop new  strategies in the fields of prevention, diagnostics  or genetics based pharmacology that can contribute  to extend the lifespan and mental health of the  elderly.\u003c\/p\u003e\u003cdiv class=\"aw-variant-hidden-subtitle-div\" id=\"aw-variant-subtitle-9783843388689\"\u003e\u003ch3\u003eCandidate gene approach\u003c\/h3\u003e\u003c\/div\u003e","brand":"Autorenwelt Shop","offers":[{"title":"Softcover - 9783843388689","offer_id":39470070661213,"sku":"9783843388689","price":49.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0940\/0622\/files\/295f9afc-7fb4-417a-a782-ce5b8270d1d7.jpg?v=1773471385","url":"https:\/\/shop.autorenwelt.de\/products\/genetic-risk-factors-in-alzheimers-disease-von-agnes-feher","provider":"Autorenwelt Shop","version":"1.0","type":"link"}