{"product_id":"genes-and-mechanisms-in-vertebrate-sex-determination-von-undefined","title":"Genes and Mechanisms in Vertebrate Sex Determination","description":"\n                                \n                \u003cp\u003eFollowing an opening chapter by the late Susumu Ohno on paralogues of sex-determining genes, the five best-studied genes essential for early mammalian gonadal development are portrayed in detail: SF-1 and WT1 and their roles in early events in gonadal development, SRY and SOX9 in testis determination, and the anti-testis gene DAX-1. Subsequent chapters look at the roles of these genes in sex determination in marsupial mammals, birds, reptiles, amphibians and fish, and review the different sex-determining mechanisms, genetic and environmental, that operate in these different vertebrate classes. Two insights emerge: one, that the same basic set of genes appears to operate during early gonadal development in all vertebrates, despite the differences in mechanisms; the other, that sex determination in vertebrates results from a complex network of regulatory interactions and not from a simple hierarchical cascade of gene actions.\u003c\/p\u003e\n                            \n            \u003cdiv class=\"aw-variant-hidden-subtitle-div\" id=\"aw-variant-subtitle-9783034877831\"\u003e\u003ch3\u003e\u003c\/h3\u003e\u003c\/div\u003e","brand":"Autorenwelt Shop","offers":[{"title":"Softcover - 9783034877831","offer_id":49592432001349,"sku":"9783034877831","price":53.49,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0940\/0622\/files\/6f3a3814-e5b0-42f6-a738-22cb6aaa148d.jpg?v=1774070359","url":"https:\/\/shop.autorenwelt.de\/products\/genes-and-mechanisms-in-vertebrate-sex-determination-von-undefined","provider":"Autorenwelt Shop","version":"1.0","type":"link"}