{"product_id":"fermented-cholesterol-lowering-drug-lovastatin-von-sadia-javed-munazzah-meraj-shazia-anwer-bukhari","title":"Fermented Cholesterol Lowering Drug (Lovastatin)","description":"\u003cp\u003eLovastatin is an inhibitor of 3-hydroxy-3methylglutaryl-coenzyme A reductase (HMG-CoA reductase), an enzyme that catalyzes the conversion of HMG-CoA to mevalonate. In western countries, the most significant cause of death is the coronary heart disease and progression of atherosclerosis which is mostly related to the hypercholesterolemia. Approximately 10.8% of all deaths are caused due to this disease. Coronary heart disease actually is a wide assortment of diseases. It has been reported that 30 million people have familial hypercholesterolemia worldwide, but less than 1% of cases are diagnosed in most countries. A lab experiment was carried out for fungal production of lovastatin in solid state fermentation. Fermentation medium was optimized by optimizing the fermentation parameters (pH, temperature, inoculum size, moisture contents etc.).\u003c\/p\u003e\u003cdiv class=\"aw-variant-hidden-subtitle-div\" id=\"aw-variant-subtitle-9783845475158\"\u003e\u003ch3\u003e\u003c\/h3\u003e\u003c\/div\u003e","brand":"Libri","offers":[{"title":"Softcover - 9783845475158","offer_id":39442454872157,"sku":"9783845475158","price":54.9,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0940\/0622\/files\/a3d3c2ab-5253-4c79-bef5-a1a334a77a5f.jpg?v=1773122397","url":"https:\/\/shop.autorenwelt.de\/products\/fermented-cholesterol-lowering-drug-lovastatin-von-sadia-javed-munazzah-meraj-shazia-anwer-bukhari","provider":"Autorenwelt Shop","version":"1.0","type":"link"}