{"product_id":"fatty-acids-and-experimental-hepatitis-von-jihan-hussein-dalia-medhat-hebatalla-fahmy","title":"Fatty acids and experimental hepatitis","description":"\u003cp\u003eHepatitis caused by virus infection, alcohol, bacteria and many hepatotoxic agents is known to be a serious clinical syndrome that could result in hepatocytes necrosis.Various models of experimental hepatitis are used; one of which is that induced by D-Galactosamine (D-GalN) .This model is identical to human viral hepatitis in both morphological and functional characters.Lipopolysaccharide (LPS) together with D-galactosamine (D-Ga1N) induce pronounced secretion of pro-inflammatory mediators by Kupffer cells which have been proved to be early hepatic injury stimulators . Omega-3 (n-3) represents a big family of fatty acids (essential fatty acids) that consists of eicosapentaenoic acid (EPA), ¿-linolenic acid (ALA) and docosahexaenoic acid (DHA) .Omega-3 and omega-6 have the ability to modulate immune system components (production, releasing and activity), therefore omega -3 was found to have anti-inflammatory role while omega -6 is characterized by a pro-inflammatory effect. Different mechanisms were suggested in this point including prostaglandin production, cell membrane fluidity and regulation of gene expression .\u003c\/p\u003e\u003cdiv class=\"aw-variant-hidden-subtitle-div\" id=\"aw-variant-subtitle-9786202011969\"\u003e\u003ch3\u003e\u003c\/h3\u003e\u003c\/div\u003e","brand":"Libri","offers":[{"title":"Softcover - 9786202011969","offer_id":39448092639325,"sku":"9786202011969","price":35.9,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0940\/0622\/files\/ceac8884-be2b-4c4c-92d6-b20cb8fe29be.jpg?v=1773727757","url":"https:\/\/shop.autorenwelt.de\/products\/fatty-acids-and-experimental-hepatitis-von-jihan-hussein-dalia-medhat-hebatalla-fahmy","provider":"Autorenwelt Shop","version":"1.0","type":"link"}