{"product_id":"factorial-design-a-comparative-study-with-and-without-use-of-software-a-comparative-factorial-design-approach-in-pharmaceutical-formulations-von-pradnya-palekar-shanbhag-priyank-parikh","title":"Factorial Design: A Comparative Study With And Without Use of Software","description":"\u003cp\u003eFactorial design as optimization technique was applied in formulation development and processing conditions of Diclofenac sodium granules. The present study involves design and evaluation of non-effervescent granules of Diclofenac sodium with excellent flow properties. In the formulation of non-effervescent granules of Diclofenac sodium, angle of repose was the dependent variable (with excellent flow) and the concentrations of binder (Povidone K-30) and lubricant (Magnesium stearate) were the two independent variables chosen at two different levels. With the help of factorial approach, a polynomial equation Y= B0 + B1X1 + B2X2 + B12X1X2 was formed. Using the polynomial equation three new formulations were selected and performed to evaluate the correlation between experimental and predicted responses. A good correlation was obtained between the experimental and the predicted values. Also the work was oriented to have a comparative study of application of factorial design with and without use of software and come up with any pros and cons of these respective ways.\u003c\/p\u003e\u003cdiv class=\"aw-variant-hidden-subtitle-div\" id=\"aw-variant-subtitle-9783659460111\"\u003e\u003ch3\u003eA Comparative Factorial Design Approach In Pharmaceutical Formulations\u003c\/h3\u003e\u003c\/div\u003e","brand":"Libri","offers":[{"title":"Softcover - 9783659460111","offer_id":39448580063325,"sku":"9783659460111","price":39.9,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0940\/0622\/files\/237293a1-85da-4a0f-8b83-fdc76e7927e1.jpg?v=1769837720","url":"https:\/\/shop.autorenwelt.de\/products\/factorial-design-a-comparative-study-with-and-without-use-of-software-a-comparative-factorial-design-approach-in-pharmaceutical-formulations-von-pradnya-palekar-shanbhag-priyank-parikh","provider":"Autorenwelt Shop","version":"1.0","type":"link"}