Benzodiazepines represent a large and important class of psychotherapeutic agents acting on the central nervous system. Due to their tranquilizer, anti-depressive and sedative properties they have become the drugs of choice for the treatment of anxiety, sleep disorders, status epilepsy, insomnia, frequent nocturnal, early morning awakenings or other convulsive disorders. This book compromises brief discussion on structure, properties and the effects of benzodiazepines, comprehensive review on sample preparation and determination of these drugs in biological samples by HPLC methods to be helpful for the researchers. Two new validated HPLC methods for the determination of 1,4-benzodiazepines and an investigation on stability of six commonly prescribed 1,4-benzodiazepines in biological samples are included. This book may be advantageous for routine determination of these drugs in forensic and clinical investigations, and applicable for the quantitative estimation in quality control in pharmaceutical formulations.
Tags: Medizin, Klinische Fächer
Taschenbuch - 9783659103971 Verlag: LAP Lambert Academic Publishing Ersterscheinung: April 2012 ISBN-13: 9783659103971 Größe: 220 mm x 150 mm x 11 mm Gewicht: 290 Gramm 184 Seiten Versandfertig in 3-5 Tagen.