{"product_id":"enantiopure-nucleosides-from-carbohydrates-von-biswajit-gopal-roy-und-sukhendu-bikas-mandal","title":"Enantiopure Nucleosides From Carbohydrates","description":"\u003cp\u003eThe design and synthesis of nucleoside analogues as  potential anticancer and antiviral agents is a very  dynamic field of research. The core objective of  this intense research is amendment in sugar and base  moieties to make the nucleoside more apt for  therapeutic response. The drug industry now a day is  giving more emphasis on chiral molecules as these  are much more specific to the target. Even the two  enantiomers of a particular substrate may interact  differently with different chiral pockets and show  different kinds of activity. So it is imperative to  devise routes to nucleosides, which yield desired  molecular structures with specific stereochemistry.  Carbohydrates with six chiral centers are nice  starting materials for this purpose.  Among the  carbohydrates, D-glucose is a useful chiral  template, as it is cheap, easily available. Three  chapters of this book is dealing with the use of  various simple and useful reactions on glucose  molecule to synthesize chiral carbocyclic (Chapter  1), heterocyclic (Chapter 2) and bicyclic (Chapter 3) nucleosides and analogues.\u003c\/p\u003e\u003cdiv class=\"aw-variant-hidden-subtitle-div\" id=\"aw-variant-subtitle-9783844392487\"\u003e\u003ch3\u003eSynthesis of Enantiomerically Pure Nucleosides and Analogues Involving Carbohydrates as Chiral Pool\u003c\/h3\u003e\u003c\/div\u003e","brand":"Autorenwelt Shop","offers":[{"title":"Softcover - 9783844392487","offer_id":39495917404253,"sku":"9783844392487","price":68.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0940\/0622\/files\/430939a6-ebb7-4f61-8b22-e40d37b5e8b2.jpg?v=1757913403","url":"https:\/\/shop.autorenwelt.de\/products\/enantiopure-nucleosides-from-carbohydrates-von-biswajit-gopal-roy-und-sukhendu-bikas-mandal","provider":"Autorenwelt Shop","version":"1.0","type":"link"}