{"product_id":"development-of-self-microemulsifying-drug-delivery-system-von-maulik-patel-sanjay-patel-und-natvarlal-patel","title":"Development of Self Microemulsifying Drug Delivery System","description":"\u003cp\u003eNearly 40% of new drug candidates exhibit low  solubility in water, which leads to poor oral  bioavailability, high intra- and inter-subject  variability and lack of dose proportionality.  Modification of the physicochemical properties,  such as salt formation and particle size reduction  of the compound may be one approach to improve the  dissolution rate of the drug. However, these  methods have their own limitations. In recent  years, much attention has focused on lipid based  formulations to improve the oral bioavailability of  poorly water soluble drugs. In fact, the most  popular approach is the incorporation of the drug  compound into inert lipid vehicles such as oils,  surfactant dispersions, self-emulsifying  formulations, emulsions and liposomes with  particular emphasis on self-microemulsifying drug  delivery systems (SMEDDS).\u003c\/p\u003e\u003cdiv class=\"aw-variant-hidden-subtitle-div\" id=\"aw-variant-subtitle-9783844331820\"\u003e\u003ch3\u003ePreparation and evaluation of Lovastatin Self Microemulsifying Drug Delivery System\u003c\/h3\u003e\u003c\/div\u003e","brand":"Autorenwelt Shop","offers":[{"title":"Softcover - 9783844331820","offer_id":39495979040861,"sku":"9783844331820","price":49.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0940\/0622\/files\/0c8773b5-4b98-485d-bb11-cf05a4e35b19.jpg?v=1776143858","url":"https:\/\/shop.autorenwelt.de\/products\/development-of-self-microemulsifying-drug-delivery-system-von-maulik-patel-sanjay-patel-und-natvarlal-patel","provider":"Autorenwelt Shop","version":"1.0","type":"link"}