{"product_id":"development-of-conducting-polymer-based-nucleic-acid-biosensors-von-nirmal-prabhakar-harpal-singh-und-bansi-d-malhotra","title":"DEVELOPMENT OF CONDUCTING POLYMER BASED NUCLEIC ACID BIOSENSORS","description":"\u003cp\u003eNucleic acid biosensors have been found to have  interesting possibilities for applications in  various fields including environmental and medical  screening. The two types of analysis used for the  nucleic acid biosensors are : (a) detection of  genotoxicants\/ DNA damage (b) detection of DNA  hybridization. For the detection of genotoxicants,  the double stranded calf thymus DNA has been  electrochemically entrapped into conducting  polymers like Polypyrrole (PPy) and Polyaniline  (PANI) films to detect chlorpyrifos and malathion.  Compared to DNA-PPy, DNA-PANI electrodes have  better detection limit for chlorpyrifos and  malathion (0.5 ppb and 0.01 ppm, respectively)  within 30s, and are stable for about 6 months.  The  PNA and DNA probes specific to M. tuberculosis have  been immobilized onto the PPy and PANI films  prepared onto ITO glass for detection of  complementary target. The obtained detection limit  is about 0.1attomole within 30s and electrodes  could detect the genomic DNA of M. tuberculosis in  serum samples up to 2.5 pg\/¿l within about 60s at  300 C and can be used 8¿9 times.\u003c\/p\u003e\u003cdiv class=\"aw-variant-hidden-subtitle-div\" id=\"aw-variant-subtitle-9783838380513\"\u003e\u003ch3\u003eApplication of Conducting polymers for detection of genotoxicants and Mycobacterium tuberculosis\u003c\/h3\u003e\u003c\/div\u003e","brand":"Autorenwelt Shop","offers":[{"title":"Softcover - 9783838380513","offer_id":39469258309725,"sku":"9783838380513","price":68.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0940\/0622\/files\/36da5351-013a-4301-97fe-b96226bc27ff.jpg?v=1774682136","url":"https:\/\/shop.autorenwelt.de\/products\/development-of-conducting-polymer-based-nucleic-acid-biosensors-von-nirmal-prabhakar-harpal-singh-und-bansi-d-malhotra","provider":"Autorenwelt Shop","version":"1.0","type":"link"}