{"product_id":"development-of-a-new-generation-of-artificial-heart-valve-von-roman-major-hrsg","title":"Development of a new generation of artificial heart valve","description":"\u003cp\u003eThe project goal is minimizing life-threatening thrombo-emboli formation in pulsatile heart assist devices by a new biomimetic heart valve design based on metal-polymer composites. Heart prostheses support patients with late-stage heart diseases towards recovery or as a bridge to transplantation. In future, they will assist gene therapy to treat myocardial infarction. Besides of deficient blood flow (stagnant zones), state-of-the-art systems with mechanical valves generate platelet activating shear due to a narrow disc-ring gap. The novel composite and valve design solve these pressing medical needs: Injection moulding of polyurethane with a fragile titanium mesh insert combines biologically optimal micro-scale flexibility with macro-stiffness for mechanical function. Added transnational value is joining knowhow in: (1) heart valve design for optimal blood flow,(2) haemo-biofunctional coatings,(3) insert injection moulding, and(4) testing, finally on the artificial patient model.\u003c\/p\u003e\u003cdiv class=\"aw-variant-hidden-subtitle-div\" id=\"aw-variant-subtitle-9786139975181\"\u003e\u003ch3\u003e\u003c\/h3\u003e\u003c\/div\u003e","brand":"Libri","offers":[{"title":"Softcover - 9786139975181","offer_id":39459886497885,"sku":"9786139975181","price":39.9,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0940\/0622\/files\/dbfcd3fe-5026-48b9-900a-88f51f86811e.jpg?v=1775190324","url":"https:\/\/shop.autorenwelt.de\/products\/development-of-a-new-generation-of-artificial-heart-valve-von-roman-major-hrsg","provider":"Autorenwelt Shop","version":"1.0","type":"link"}