{"product_id":"detection-of-anti-malarial-igg-igg-subclasses-in-sudanies-patients-von-mona-mohamed-el-toum-el-sheisk","title":"Detection of Anti malarial IgG\/IgG subclasses in sudanies patients","description":"\u003cp\u003eMerozoite surface protein MSP2 is avaccine  candidate antigen of Plasmodium falciparum that is  polymorphic in natural populations. In this study we  aimed to investigate whether malaria infection in  associated with anti-malaria specific IgG, using  recombinant proteins derived from the two major  allelic types of MSP2 and ABO blood group. The conclusion is the Higher anti-malarial IgG1,  IgG3, IgG2 and lower levels of IgG4 were associated  with reduced risk of malaria infection. IgG2 is  activator of the classical complement pathway,  Fc¿RIIa H131 is essential for handling IgG2 immune  complexes. These data suggest that an MSP2 based  vaccine should be designed to induce high level  antibody responses against the different MSP2 types  present globally in P. falciparum populations and  that MSP2 could be combined with other P. falciparum  antigens to form a multi-component malaria vaccine.\u003c\/p\u003e\u003cdiv class=\"aw-variant-hidden-subtitle-div\" id=\"aw-variant-subtitle-9783843381789\"\u003e\u003ch3\u003eDetection of Antimalarial IgG\/IgG subclass in relationship to ABO blood group and haematological changes in Sudanese Patients\u003c\/h3\u003e\u003c\/div\u003e","brand":"Autorenwelt Shop","offers":[{"title":"Softcover - 9783843381789","offer_id":39497030926429,"sku":"9783843381789","price":49.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0940\/0622\/files\/c53b7236-bcb6-48c7-92ef-8982b7e088b9.jpg?v=1737530564","url":"https:\/\/shop.autorenwelt.de\/products\/detection-of-anti-malarial-igg-igg-subclasses-in-sudanies-patients-von-mona-mohamed-el-toum-el-sheisk","provider":"Autorenwelt Shop","version":"1.0","type":"link"}