{"product_id":"design-synthesis-and-evaluation-of-some-novel-heterocyclic-compounds-von-parag-rabara-shashikant-pattan","title":"Design, Synthesis and Evaluation of Some Novel Heterocyclic Compounds","description":"\u003cp\u003eIn the present research work a new series of 1,3,4-oxadiazole \u0026amp; pyrazolone derivatives have been synthesized. 2-mercapto-1,3,4-oxadiazole derivatives were synthesized by reacting corresponding acid hydrazide with carbon disulfide followed by condensing the active hydrogen atom of 2-mercapto group of 5-aryl-2-mercapto-1,3,4-oxadiazole with 2-chloro pyridine, 4-chloro aniline \u0026amp; epichlorohydrine to give 5-aryl-2-(substituted aryl ylthio)-1,3,4-oxadiazole derivatives(A1-3, B1-4). 5-(substituted aryl)-1,3,4-oxadiazole derivatives were synthesized by reacting salicylic acid hydrazide with aromatic acid to give 5-(2-hydroxy phenyl)-2-aryl-1,3,4-oxadiazole derivatives (A4-6): 3-methyl-pyrazol-5(4H)-one derivatives were synthesized by reacting corresponding acid hydrazide with ethyl acetoacetate to give 1-(substituted aryl)-3-methyl-1H-pyrazol-5(4H)-one. Followed by condensing the active hydrogen atom of ¿CH2- of pyrazolone with Isonicotinic acid hydrazine\/ p-amino salicylic acid\/ sulfanilamide \/ 5-amino tetrazole \/ pyrazinoic acid hydrazide \/ 2-amino pyrazine to give corresponding pyrazolone derivatives (A7-11, B5-9).\u003c\/p\u003e\u003cdiv class=\"aw-variant-hidden-subtitle-div\" id=\"aw-variant-subtitle-9783659873072\"\u003e\u003ch3\u003e\u003c\/h3\u003e\u003c\/div\u003e","brand":"Libri","offers":[{"title":"Softcover - 9783659873072","offer_id":39434986356829,"sku":"9783659873072","price":39.9,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0940\/0622\/files\/366d17c5-9964-4497-96f2-b15904fd013f.jpg?v=1769752080","url":"https:\/\/shop.autorenwelt.de\/products\/design-synthesis-and-evaluation-of-some-novel-heterocyclic-compounds-von-parag-rabara-shashikant-pattan","provider":"Autorenwelt Shop","version":"1.0","type":"link"}