{"product_id":"defects-in-t-cell-trafficking-and-resistance-to-cancer-immunotherapy-von-emmanuel-donnadieu-hrsg","title":"Defects in T Cell Trafficking and Resistance to Cancer Immunotherapy","description":"This volume focuses on recent advances in understanding T cells as key players in antitumor immune responses, and as a result T cell-based immunotherapy is starting to transform the treatment of advanced cancers. However, despite recent successes, many patients with cancer fail to respond to these treatments. Defective migration of T cells into and within tumors is considered as an important resistance mechanism to cancer immunotherapy.The volume includes three sections. The first section covers general knowledge about T cell trafficking during a normal immune response but also during tumor development. The second section provides an in-depth description of the different obstacles that prevent T cells from migrating and contacting tumor cells. The third section explores therapeutic strategies to improve trafficking of T cells into tumors and, thus, to enhance the effectiveness of cancer immunotherapy.\u003cdiv class=\"aw-variant-hidden-subtitle-div\" id=\"aw-variant-subtitle-9783319422213\"\u003e\u003ch3\u003e\u003c\/h3\u003e\u003c\/div\u003e","brand":"Libri","offers":[{"title":"Hardcover - 9783319422213","offer_id":28577337409629,"sku":"9783319422213","price":106.99,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0940\/0622\/files\/83929ab9-4001-4dbe-8f83-4dec5f7656e2.jpg?v=1775190063","url":"https:\/\/shop.autorenwelt.de\/products\/defects-in-t-cell-trafficking-and-resistance-to-cancer-immunotherapy-von-emmanuel-donnadieu-hrsg","provider":"Autorenwelt Shop","version":"1.0","type":"link"}