{"product_id":"computational-drug-designing-of-mray-in-pathogenic-atherosclerosis-von-kanipakam-hema","title":"Computational Drug Designing of MraY in Pathogenic Atherosclerosis","description":"\u003cp\u003eAtherosclerosis is a multifactorial vascular inflammatory disease which is one of top most common cause of deaths around worldwide. Implementing Bioinformatics tools, phospho-MurNAc-pentapeptide translocase (MraY) was identified as one of the crucial drug targets against eleven pathogens causing atherosclerosis. MraY is an essential enzyme membrane which plays a crucial role in catalyzing the essential step of bacterial cell wall biosynthesis in Gram-negative bacteria. The enzyme MraY mainly involves in the peptidoglycan biosynthesis which is unique and important for the survival of pathogens. Therefore, by blocking MraY function with lead 1 would dissolve the structural integrity, flexibility and rigidity of the cell wall and expose the pathogens to osmotic lysis and hinders the proliferation of eleven pathogens causing atherosclerosis. Hence, lead 1 will provide a framework for developing new antagonists against the eleven pathogens causing atherosclerosis.\u003c\/p\u003e\u003cdiv class=\"aw-variant-hidden-subtitle-div\" id=\"aw-variant-subtitle-9786200214232\"\u003e\u003ch3\u003e\u003c\/h3\u003e\u003c\/div\u003e","brand":"Libri","offers":[{"title":"Softcover - 9786200214232","offer_id":39464579563613,"sku":"9786200214232","price":39.9,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0940\/0622\/files\/f323a7ae-678a-40f1-9d0f-df9687a74964.jpg?v=1770100721","url":"https:\/\/shop.autorenwelt.de\/products\/computational-drug-designing-of-mray-in-pathogenic-atherosclerosis-von-kanipakam-hema","provider":"Autorenwelt Shop","version":"1.0","type":"link"}