{"product_id":"computational-analysis-of-stmads11-mads-box-regulatory-elements-analysis-underlying-expression-divergence-von-tajammul-hussain-muhammad-ramzan-khan","title":"Computational analysis of STMADS11 MADS-box regulatory elements","description":"\u003cp\u003eFunctions of orthologs may diverge during evolution either due to alteration of cis-regulatory elements or changes in the coding regions. The STMADS11 superclade MADS-box genes play diverse roles in plants; implicated in vegetative development, phase transition, floral meristem identity, male fertility and inflated calyx. Phylogenetic reconstruction revealed three distinct clades comprising MPF1-like, MPF2-like and SVP-like. Expression analysis indicated inter and intra-clade expression divergence with regard to their expression in vegetative and floral tissues. The MADS-domain HCTs were predominantly located in the promoter regions. These MADS-domain HCTs are located in the vicinity of the TSS seemed to be involved in regulating expression in sepal, particularly in case of MPF2-like clade. Phylogenetic foot printing of -2kb STMADS11 promoter sequences highlighted two conserve regions; immediately upstream of TSS site and proximal to TSS. These regions have evolved under negative selection. A comprehensive understanding of the role of STMADS11 cis-regulatory elements in expression divergence is though enigmatic, this study highlights the significance of cis-regulatory elements.\u003c\/p\u003e\u003cdiv class=\"aw-variant-hidden-subtitle-div\" id=\"aw-variant-subtitle-9783847326717\"\u003e\u003ch3\u003eanalysis underlying expression divergence\u003c\/h3\u003e\u003c\/div\u003e","brand":"Libri","offers":[{"title":"Softcover - 9783847326717","offer_id":39451368751197,"sku":"9783847326717","price":54.9,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0940\/0622\/files\/9c93f465-b014-4ad9-ba60-6a20c1db1e84.jpg?v=1773209945","url":"https:\/\/shop.autorenwelt.de\/products\/computational-analysis-of-stmads11-mads-box-regulatory-elements-analysis-underlying-expression-divergence-von-tajammul-hussain-muhammad-ramzan-khan","provider":"Autorenwelt Shop","version":"1.0","type":"link"}