{"product_id":"complement-regulatory-proteins-in-breast-cancer-von-zahra-madjd-und-lindy-durrant","title":"Complement Regulatory Proteins in Breast Cancer","description":"\u003cp\u003eChoosing appropriate molecular markers is an  intriguing area of oncology research to find out  individualized treatments. Targeted therapy, which  consists of therapeutic agents directed at specific  molecules, is contemporary approach against cancers.  This book looks at the impact of immune-editing on  the aetiology of breast cancer to determine if this  would provide novel prognostic markers for patients''  management. The expression of membrane CRPs (mCRP)  CD59, CD55, CD46, also HLA class-I was measured on  an extensive series of breast cancer tissues, using  tissue microarrays.  Tissue microarrays linked to good  clinicopathological databases with a long term  follow up are useful tools to determine new  prognostic indicators that can be used in future  clinical management. Both CD59 and HLA class-I were  identified to be independent markers of prognosis.  They could be used in addition to Nottingham  Prognostic Index to help further stratify patients  for adjuvant therapy. Patients lacking CD59 but  expressing HLA could be candidates for aggressive  chemotherapy as they have a poor predicted outcome.\u003c\/p\u003e\u003cdiv class=\"aw-variant-hidden-subtitle-div\" id=\"aw-variant-subtitle-9783838337692\"\u003e\u003ch3\u003eExpression of Complement Regulatory Proteins CD59, CD55, CD46 and MHC Class I Molecules on Breast  Carcinomas\u003c\/h3\u003e\u003c\/div\u003e","brand":"Autorenwelt Shop","offers":[{"title":"Softcover - 9783838337692","offer_id":39499072143453,"sku":"9783838337692","price":79.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0940\/0622\/files\/c1dd3430-b8be-444d-91b8-19c790a77b9a.jpg?v=1757655156","url":"https:\/\/shop.autorenwelt.de\/products\/complement-regulatory-proteins-in-breast-cancer-von-zahra-madjd-und-lindy-durrant","provider":"Autorenwelt Shop","version":"1.0","type":"link"}