{"product_id":"cancer-stem-cell-resistance-to-targeted-therapy-von-soldano-ferrone-cristina-maccalli-matilde-todaro-soldano-ferrone-hrsg","title":"Cancer Stem Cell Resistance to Targeted Therapy","description":"\n                                \n                \u003cp\u003e\u003c\/p\u003e\n                                \n                \u003cp\u003eThis book represents an up-dated summary of the state of the art of the characterization of cancer stem cell\/ cancer initiating cell (CSC\/CIC) properties.  An overview of the definition and biological properties of CSCs\/CICs as well as the role of these cells in determining the resistance to standard and immune-based therapies is provided. It also discusses limitations in the achievement of a definitive biological characterization of CSCs\/CICs due to their high extent of plasticity and heterogeneity that is also mutually driven by the interaction of these cells with the tumor microenvironment. The limitations in targeting CSCs\/CICs with immunotherapy are also explained together with explorative combination approaches that could increase the susceptibility of these cells to the recognition by immune cells. \u003c\/p\u003e\n                                \n                \n                \u003cp\u003eThis book is conceived for a broad audience, including students, teachers, scientific experts. The critical revision of available results in terms of immunological profile of CSCs\/CICs and the efficacy in targeting these cells by immunological approaches, results in a comprehensive and up to date recapitulation of the field and provides interesting suggestions on how to focus future investigations in order to assess the role of CSCs\/CICs as prognostic and predictive biomarkers of responsiveness to therapies for cancer patients.\u003c\/p\u003e\n                                \n                \u003cp\u003e\u003c\/p\u003e\n                            \n            \u003cdiv class=\"aw-variant-hidden-subtitle-div\" id=\"aw-variant-subtitle-9783030166236\"\u003e\u003ch3\u003e\u003c\/h3\u003e\u003c\/div\u003e\u003cdiv class=\"aw-variant-hidden-subtitle-div\" id=\"aw-variant-subtitle-9783030166267\"\u003e\u003ch3\u003e\u003c\/h3\u003e\u003c\/div\u003e","brand":"Libri","offers":[{"title":"Hardcover - 9783030166236","offer_id":28473869992029,"sku":"9783030166236","price":106.99,"currency_code":"EUR","in_stock":true},{"title":"Softcover - 9783030166267","offer_id":39418877050973,"sku":"9783030166267","price":106.99,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0940\/0622\/files\/73461_a4bc1042-c472-4d95-969e-92f302ab0030.jpg?v=1786507501","url":"https:\/\/shop.autorenwelt.de\/products\/cancer-stem-cell-resistance-to-targeted-therapy-von-soldano-ferrone-cristina-maccalli-matilde-todaro-soldano-ferrone-hrsg","provider":"Autorenwelt Shop","version":"1.0","type":"link"}