{"product_id":"ca19-9-in-differentiating-benign-and-malignant-obstructive-jaundice-von-mohammad-golam-azam-rokanuzzaman-bhuyian-2","title":"CA19.9 in differentiating benign and malignant obstructive jaundice","description":"\u003cp\u003eSerum carbohydrate antigen 19-9 (CA 19-9), a tumour marker for malignancies of the hepatobiliary tract and pancreas, frequently elevated in a number of non-malignant conditions that are associated with jaundice. The CA 19-9 tends to normalize the following restoration of biliary drainage. Sixty three patients presented with obstructive jaundice on the basis of clinical and imaging methods with elevated CA 19-9 were studied. Diagnostic accuracy of CA19-9 in the detection of malignancy was estimated by the receiver operating characteristic (ROC) curve. Median value of CA 19-9 in malignant cases was higher (1000 U\/ml) than benign cases (93 U\/ml) (p=0.001). After biliary drainage serum CA19-9 levels normalized in 15(50%) benign and 1(3%) malignant cases (p=0.001). The AUC of CA 19-9 was 0.825. Diagnostic accuracy of CA 19-9 was observed more at cut off value 200 U\/ml. Deranged CA19-9 is frequently observed in benign conditions with jaundice and shown to normalize following improvement of biliary drainage. Caution is necessary in the interpretation of an elevated serum CA 19-9 value as a marker for malignancy, especially in patients with benign cholestasis.\u003c\/p\u003e\u003cdiv class=\"aw-variant-hidden-subtitle-div\" id=\"aw-variant-subtitle-9783330337107\"\u003e\u003ch3\u003e\u003c\/h3\u003e\u003c\/div\u003e","brand":"Libri","offers":[{"title":"Softcover - 9783330337107","offer_id":39428371447901,"sku":"9783330337107","price":23.9,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0940\/0622\/files\/135367cd-cfa3-4f05-b969-a9ac6080f2bf.jpg?v=1768628067","url":"https:\/\/shop.autorenwelt.de\/products\/ca19-9-in-differentiating-benign-and-malignant-obstructive-jaundice-von-mohammad-golam-azam-rokanuzzaman-bhuyian-2","provider":"Autorenwelt Shop","version":"1.0","type":"link"}