{"product_id":"brca1-and-brca2-mutations-hrsg-von-mani-t-valarmathi","title":"BRCA1 and BRCA2 Mutations","description":"\u003cp\u003eMutations in the BRCA1\/2 genes are the most common cause of hereditary breast and ovarian cancer (HBOC), and HBOC is an autosomal dominant cancer predisposition syndrome. Individuals with HBOC have a high risk for breast and ovarian cancers and a moderate risk for other cancers, such as prostate, pancreatic, melanoma, and fallopian tube cancers. The goal of screening individuals at high risk of familial cancer is either prevention (such as a change in lifestyle or diet) or early detection of cancer. The identification of BRCA mutation carriers is important, since increased surveillance, drug therapy, and prophylactic surgery can reduce cancer-related morbidity and mortality. In recent years, there has been substantial development in BRCA-associated hereditary breast and\/or breast-ovarian cancer research and its clinical applications. In this context, this book consolidates the recent advances in BRCA-related cancer biology and therapeutics, covering a wide spectrum of interrelated topics. Chapters cover a wide range of topics, such as BRCA discovery, BRCA structure and function, BRCA-associated cancers, BRCA genetic testing and counselling, and more. This book is a valuable resource not only for medical and allied health students but also for researchers, clinical and nurse geneticists, genetic counselors, and physician assistants.\u003c\/p\u003e\u003cdiv class=\"aw-variant-hidden-subtitle-div\" id=\"aw-variant-subtitle-9781803568065\"\u003e\u003ch3\u003eDiagnostic and Therapeutic Implications\u003c\/h3\u003e\u003c\/div\u003e","brand":"Autorenwelt Shop","offers":[{"title":"Hardcover - 9781803568065","offer_id":58920390295877,"sku":"9781803568065","price":135.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0940\/0622\/files\/73461_8ec36236-f852-4e9a-9fb6-2a9758b124e8.jpg?v=1787198770","url":"https:\/\/shop.autorenwelt.de\/products\/brca1-and-brca2-mutations-hrsg-von-mani-t-valarmathi","provider":"Autorenwelt Shop","version":"1.0","type":"link"}