{"product_id":"beta-thalassemia-major-and-associated-complications-von-naouel-guirat-mohamed-bejaoui","title":"Beta-thalassemia major and associated complications","description":"\u003cp\u003eBeta-thalassemia major (TM) remains to be one of the major health problems particularly in developing countries. Tunisia is a part of the Mediterranean countries mostly affected by this disease which is highly concentrated in small towns in families with low-income earners. The main objectives of this study are to provide a description of the demographic, clinical features and transfusion-related complications in patients with TM living in Tunisia. A standardized questionnaire was sent to clinicians throughout 33 different medical institutions caring for thalassemic patients. 391 transfusion dependant thalassemic patients with a median age of 10.7 years (range 3 months- 31 years) were included in the study. The majority originated from the north west of the country. A moderate iron overload between 1501 and 2500 ng\/ml was found in 61patients, while 81 patients (26.9%) had a ferritin level more than 2500 ng\/ml and greater than 5000ng\/ml in 21 patients (6.9%). 51 patients died from complications related to their disease. Heart failure was the main cause of death. The incidence of cardiac, endocrine, and infectious complications will be reviewed.\u003c\/p\u003e\u003cdiv class=\"aw-variant-hidden-subtitle-div\" id=\"aw-variant-subtitle-9786200226464\"\u003e\u003ch3\u003e\u003c\/h3\u003e\u003c\/div\u003e","brand":"Libri","offers":[{"title":"Softcover - 9786200226464","offer_id":39464866840669,"sku":"9786200226464","price":39.9,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0940\/0622\/files\/374be627-6a1b-47ad-8e87-008a17010a66.jpg?v=1757658409","url":"https:\/\/shop.autorenwelt.de\/products\/beta-thalassemia-major-and-associated-complications-von-naouel-guirat-mohamed-bejaoui","provider":"Autorenwelt Shop","version":"1.0","type":"link"}