{"product_id":"at1a-mrna-expression-in-rat-cardiac-tissue-von-alesha-sewnath","title":"AT1a mRNA expression in rat cardiac tissue","description":"\u003cp\u003eAnnually 9.6 million cardiovascular related deaths  occur in developing countries.  AT1 receptor  antagonists such as Losartan¿ block Ang II actions  in vitro and in vivo, although the molecular  mechanism remains unknown.  The identification of  putative AT1 receptor blockers in plants and their  mode of action remain elusive. Molecular techniques  such as Real-time PCR provides a reliable and  accurate method for use in gene expression studies.   This book looks at the vivo mechanisms of a plant  compound, compared to a commercial hypertension drug  Losartan¿, by studying their effects on AT1 mRNA  gene expression in rat cardiac tissue. Findings from  this book illustrate that AT1 gene expression is  related to the tissue-specific action of these drugs  in salt-sensitive hypertension. Analyses and  research from this book may assist in providing  insight to those interested in molecular techniques  specifically Real Time PCR used in medical research,  to those interested in hypertension and research in  this area.\u003c\/p\u003e\u003cdiv class=\"aw-variant-hidden-subtitle-div\" id=\"aw-variant-subtitle-9783838376646\"\u003e\u003ch3\u003eBenefits of RT- PCR in gene expression profiling\u003c\/h3\u003e\u003c\/div\u003e","brand":"Autorenwelt Shop","offers":[{"title":"Softcover - 9783838376646","offer_id":39498963976285,"sku":"9783838376646","price":49.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0940\/0622\/files\/574cf7b5-c3e7-4f96-bffd-b2015207d6f6.jpg?v=1757654687","url":"https:\/\/shop.autorenwelt.de\/products\/at1a-mrna-expression-in-rat-cardiac-tissue-von-alesha-sewnath","provider":"Autorenwelt Shop","version":"1.0","type":"link"}