{"product_id":"aspects-of-renal-disease-progression-von-flaviu-bob","title":"ASPECTS OF RENAL DISEASE PROGRESSION","description":"\u003cp\u003eChronic kidney disease has a continuously increasing  prevalence, associated with multiple comorbidities,  that in an increased proportion of patients shows a  progressive evolution. Knowing the factors involved  in the progression of the chronic kidney disease can  impose different therapeutic strategies. The final  common pathway for almost all forms of renal disease  is renal fibrosis. In order to better understand the  progression of chronic kidney disease, it is  mandatory to present the mechanisms of fibrogenesis,  both at glomerular and at the tubulo-interstitial  level, and also to find out which treatment targets  can be used in order to prevent or reverse this  process. After showing data regarding fibrosis, the  following chapters will present the main factors  involved in the progression of renal disease:  arterial hypertension and the renin- angiotensin-  aldosterone system, proteinuria, metabolic  disorders, anemia, smoking, salt intake and the  protective effect of alkali therapy. For an evidence- based approach the results from the main clinical  trials that involve these progression factors are  also be briefly presented.\u003c\/p\u003e\u003cdiv class=\"aw-variant-hidden-subtitle-div\" id=\"aw-variant-subtitle-9783844327205\"\u003e\u003ch3\u003eA CLINICAL APPROACH\u003c\/h3\u003e\u003c\/div\u003e","brand":"Autorenwelt Shop","offers":[{"title":"Softcover - 9783844327205","offer_id":39470135214173,"sku":"9783844327205","price":49.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0940\/0622\/files\/2c8f1979-41c8-4614-88af-d6c077b623cc.jpg?v=1759036929","url":"https:\/\/shop.autorenwelt.de\/products\/aspects-of-renal-disease-progression-von-flaviu-bob","provider":"Autorenwelt Shop","version":"1.0","type":"link"}