{"product_id":"applications-of-nitropyridine-isocyanates-von-jarle-holt","title":"Applications of nitropyridine isocyanates","description":"\u003cp\u003eBased on new methodology for nitration of pyridine  developed by Professor Jan Bakke and coworkers at  NTNU, a whole range of substituted nitropyridines  are now readily available. Novel reactions with  nitropyridine carbamates, amides and carboxylates  are described in this work. Isocyanates constitute  an important class of compounds in organic chemistry  and undergo a series of reactions. Heterocyclic  isocyanates, however, haven''t received the same  attention due to their instability and high  reactivity. The study of nitropyridine isocyanates  in cycloaddition reactions with azides, pyridine  N-oxides and ketenes demonstrate their potential.  Aromatic nucleophilic substitution of the nitro  group and acid-catalyzed cyclization reactions of  nitropyridine carbamates leading to the biologically  active imidazopyridinone is also presented. The  facile preparation of triazolopyridine and its  application in the acylation of amines was also  investigated. It proved to be more effective than  the commercially available benzotriazole. This work  is aimed at those interested in the applications of  novel nitropyridine derivatives in organic chemistry.\u003c\/p\u003e\u003cdiv class=\"aw-variant-hidden-subtitle-div\" id=\"aw-variant-subtitle-9783838398235\"\u003e\u003ch3\u003eNitropyridine carbamates, amides and carboxylates in heterocyclic chemistry\u003c\/h3\u003e\u003c\/div\u003e","brand":"Autorenwelt Shop","offers":[{"title":"Softcover - 9783838398235","offer_id":39497033875549,"sku":"9783838398235","price":49.0,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0940\/0622\/files\/c6970137-aa3e-48a4-b11b-40547e903038.jpg?v=1765261678","url":"https:\/\/shop.autorenwelt.de\/products\/applications-of-nitropyridine-isocyanates-von-jarle-holt","provider":"Autorenwelt Shop","version":"1.0","type":"link"}