{"product_id":"advanced-glycation-inhibitory-potential-of-certain-antidiabetic-plants-von-amteshwar-jaggi-varun-parkash-nirmal-singh","title":"Advanced glycation inhibitory potential of certain antidiabetic plants","description":"\u003cp\u003eThe present study was designed to investigate the antiglycation potential of hydro-alcoholic and alkaloidal fractions of selected plants. Seeds of Trigonella foenum-graecum, bulbs of Allium sativum, fruits of Momordica charantia. and leaves of Gymnema sylvestre were selected. The protein glycation inhibitory activity of these plants was evaluated using glucose-bovine serum albumin assay. Among the hydroalcoholic extracts, Trigonella-foenum graecum showed highest antiglycation activity (IC50 = 53.53 ± 1.24 µg\/ml) followed by Allium sativum (IC50 = 68.36 ± 1.56 µg\/ml), Momordica charantia (IC50 = 85.16 ± 1.87 µg\/ml) and Gymnema sylvestre (IC50 = 103.66 ± 2.09 µg\/ml). Among the alkaloidal fractions, the highest antiglycation activity was shown by Trigonella-foenum graecum (IC50 = 31.56 ± 1.36 µg\/ml) followed by Allium sativum (IC50 = 40.46 ± 1.59 µg\/ml), Momordica charantia (IC50 = 54.8 ± 2.12 µg\/ml) and Gymnema sylvestre (IC50 = 64.50 ± 1.73 µg\/ml). Aminoguanidine, a standard drug, showed 100% inhibition (IC50 = 22.45 ± 1.89 µg\/ml). Alkaloidal extracts of these plants possess antiglycation activity and may be explored in diabetic complications\u003c\/p\u003e\u003cdiv class=\"aw-variant-hidden-subtitle-div\" id=\"aw-variant-subtitle-9783659566332\"\u003e\u003ch3\u003e\u003c\/h3\u003e\u003c\/div\u003e","brand":"Libri","offers":[{"title":"Softcover - 9783659566332","offer_id":39434292265053,"sku":"9783659566332","price":39.9,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0940\/0622\/files\/13dd3c7c-db17-4e34-9975-71ade735dc9f.jpg?v=1769926495","url":"https:\/\/shop.autorenwelt.de\/products\/advanced-glycation-inhibitory-potential-of-certain-antidiabetic-plants-von-amteshwar-jaggi-varun-parkash-nirmal-singh","provider":"Autorenwelt Shop","version":"1.0","type":"link"}