{"product_id":"acid-sphingomyelinase-deficiency-enhances-myelin-repair-von-marwan-chami","title":"Acid sphingomyelinase deficiency enhances myelin repair","description":"\u003cp\u003eIn this study, we investigated the role of acid sphingomyelinase in demyelination and myelin repair by inducing acute and chronic demyelination with 5- or 12-week cuprizone treatment, followed by a 2-week cuprizone withdrawal phase to allow myelin repair.Our findings suggest that acid sphingomyelinase plays a significant role in myelin repair, and its inhibition by amitriptyline may constitute a novel therapeutic approach for multiple patients.\u003c\/p\u003e\u003cdiv class=\"aw-variant-hidden-subtitle-div\" id=\"aw-variant-subtitle-9783330344778\"\u003e\u003ch3\u003e\u003c\/h3\u003e\u003c\/div\u003e","brand":"Libri","offers":[{"title":"Softcover - 9783330344778","offer_id":39419878768733,"sku":"9783330344778","price":35.9,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0940\/0622\/files\/51843613-cb18-484e-b74e-1fc28d69a08a.jpg?v=1770096937","url":"https:\/\/shop.autorenwelt.de\/products\/acid-sphingomyelinase-deficiency-enhances-myelin-repair-von-marwan-chami","provider":"Autorenwelt Shop","version":"1.0","type":"link"}