{"product_id":"the-effects-of-vitamins-on-dna-and-rna-structures-and-dynamics-von-heidar-ali-tajmir-riahi","title":"The Effects of Vitamins on DNA and RNA Structures and Dynamics","description":"\u003cp\u003eThe important role of vitamins is well known with regard to human health and disease. In this book, we review the effects of vitamins, A, B and C on the structure and dynamics of DNA and RNA. The conjugations of vitamin A (retinol and retinoic acid), vitamin B (folic acid) and vitamin C (L-ascorbic acid) by DNA and tRNA were analyzed. The loading efficacies of these vitamins with DNA and RNA were compared in solution. Vitamins bind nucleic acids via hydrophilic, hydrophobic and H-bonding contacts with vitamin C forming more stable DNA and tRNA adducts. The loading efficacies of these vitamins were from 40% to 60%. Vitamins induce major DNA and RNA structural changes, while biopolymers remain in native conformations.\u003c\/p\u003e\u003cdiv class=\"aw-variant-hidden-subtitle-div\" id=\"aw-variant-subtitle-9786131554377\"\u003e\u003ch3\u003e\u003c\/h3\u003e\u003c\/div\u003e","brand":"Autorenwelt Shop","offers":[{"title":"Softcover - 9786131554377","offer_id":40149120385117,"sku":"9786131554377","price":39.9,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0940\/0622\/files\/13ec247f-5446-43a9-87c5-1e134a9bbd25.jpg?v=1773732796","url":"https:\/\/shop.autorenwelt.de\/en\/products\/the-effects-of-vitamins-on-dna-and-rna-structures-and-dynamics-von-heidar-ali-tajmir-riahi","provider":"Autorenwelt Shop","version":"1.0","type":"link"}